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Plasma biomarkers of neurodegeneration in patients with Parkinson's disease and dementia with Lewy bodies and at-risk individuals of Lewy body disease in the NaT-PROBE cohort

2023-12-04 neurology Title + abstract only
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BackgroundComorbid Alzheimers disease (AD) neuropathology is common in Lewy body disease (LBD); however, AD comorbidity in the prodromal phase of LBD remains unclarified. This study investigated AD comorbidity in the prodromal and symptomatic phases of LBD by analysing plasma biomarkers in patients with Parkinsons disease (PD) and dementia with Lewy bodies (DLB) and at-risk individuals of LBD (NaT-PROBE cohort). MethodsPatients with PD (PD group, n=84) and DLB (DLB group, n=16) and individuals ...

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