Back

An agent based model (ABM) to reproduce the boolean logic behaviour of neuronal self organized communities through pulse delay modulation and generation of logic gates

Irastorza, L.; Benitez, J. M.; Montans, F.; Saucedo-Mora, L.

2023-11-14 bioengineering
10.1101/2023.11.10.566538 bioRxiv
Show abstract

The human brain is arguably the most complex "machine" to ever exist. Its detailed functioning is yet to be fully understood, let alone modeled. Neurological processes have logical signal-processing aspects and biophysical aspects, and both affect the brain structure, functioning and adaptation. Mathematical approaches based on both information and graph theory have been extensively used in an attempt to approximate its biological functioning, along with Artificial Intelligence approaches inspired by its logical functioning. In this article, we present an approach to model some aspects of the brain learning and signal processing, mimicking the metastability and backpropagation found in the real brain while also accounting for neuroplasticity. Several simulations are carried out with this model, to demonstrate how dynamic neuroplasticity, neural inhibition and neurons migration can remodel the brain logical connectivity to syncronize signal processing and obtain target latencies. This work demonstrates the importance of dynamic logical and biophysical remodelling in brain plasticity.

Matching journals

The top 6 journals account for 50% of the predicted probability mass.

1
PLOS ONE
5266 papers in training set
Top 11%
18.0%
2
Neuroinformatics
46 papers in training set
Top 0.1%
6.5%
3
Biosystems
31 papers in training set
Top 0.1%
6.5%
4
IEEE Access
35 papers in training set
Top 0.1%
6.5%
5
Neurocomputing
13 papers in training set
Top 0.1%
6.5%
6
Frontiers in Computational Neuroscience
60 papers in training set
Top 0.2%
6.1%
50% of probability mass above
7
PLOS Computational Biology
1863 papers in training set
Top 7%
5.0%
8
Scientific Reports
3612 papers in training set
Top 28%
3.9%
9
Computers in Biology and Medicine
128 papers in training set
Top 1.0%
3.9%
10
Chaos, Solitons & Fractals
32 papers in training set
Top 0.3%
3.1%
11
Royal Society Open Science
214 papers in training set
Top 2%
2.3%
12
Network Neuroscience
126 papers in training set
Top 0.8%
2.1%
13
Computer Methods and Programs in Biomedicine
28 papers in training set
Top 0.5%
1.7%
14
International Journal for Numerical Methods in Biomedical Engineering
14 papers in training set
Top 0.2%
1.5%
15
Frontiers in Neuroscience
256 papers in training set
Top 4%
1.5%
16
Frontiers in Physiology
106 papers in training set
Top 1%
1.5%
17
Frontiers in Bioengineering and Biotechnology
98 papers in training set
Top 2%
1.1%
18
Biomedical Signal Processing and Control
22 papers in training set
Top 0.6%
1.0%
19
Bulletin of Mathematical Biology
92 papers in training set
Top 1%
1.0%
20
Journal of Neural Engineering
221 papers in training set
Top 2%
0.9%
21
Neural Computation
39 papers in training set
Top 0.8%
0.8%
22
European Journal of Neuroscience
189 papers in training set
Top 4%
0.8%
23
Journal of The Royal Society Interface
235 papers in training set
Top 4%
0.8%
24
Sensors
43 papers in training set
Top 1%
0.8%
25
Journal of Theoretical Biology
162 papers in training set
Top 2%
0.8%
26
BMC Bioinformatics
457 papers in training set
Top 6%
0.6%
27
Computational and Structural Biotechnology Journal
242 papers in training set
Top 8%
0.6%
28
Heliyon
152 papers in training set
Top 10%
0.6%
29
IEEE Transactions on Neural Systems and Rehabilitation Engineering
49 papers in training set
Top 1%
0.6%
30
SoftwareX
15 papers in training set
Top 0.4%
0.6%