Back
Top 15%
11.1%
#1
10.3%
Top 14%
7.3%
Top 68%
7.3%
Top 6%
5.6%
Top 0.4%
4.7%
Top 2%
3.6%
Top 5%
3.6%
Top 6%
2.0%
Top 3%
1.8%
Top 4%
1.8%
Top 14%
1.8%
Top 2%
1.8%
Top 2%
1.5%
Top 2%
1.3%
Top 8%
1.3%
Top 5%
1.1%
Top 3%
0.9%
Top 17%
0.9%
Top 10%
0.9%
Top 1%
0.9%
Top 9%
0.7%
Top 16%
0.7%
Top 0.5%
0.7%
Top 15%
0.7%
Top 7%
0.7%
Top 15%
0.7%
Top 4%
0.7%
Top 12%
0.7%
Top 22%
0.7%
From Genomics Data to Causality: An Integrated Pipeline for Mendelian Randomization
2023-11-04
epidemiology
Title + abstract only
View on medRxiv
Show abstract
BackgroundMendelian randomization (MR) has emerged as a valuable tool for causal inference in genetic epidemiology. Existing MR methods have issues related to pleiotropy and offer limited comprehensiveness. Here, we introduce an integrated MR analysis pipeline designed for GWAS summary statistics data. Our pipeline integrates feature selection, harmonization, and checkpoint mechanisms to improve the accuracy and reliability of MR analysis. MethodsIn classical GWAS, the p-value threshold usually...
Predicted journal destinations
1
Scientific Reports
701 training papers
2
Bioinformatics
24 training papers
3
Nature Communications
483 training papers
4
PLOS ONE
1737 training papers
5
eLife
262 training papers
6
PLOS Genetics
39 training papers
7
International Journal of Epidemiology
65 training papers
8
PLOS Computational Biology
141 training papers
9
The American Journal of Human Genetics
77 training papers
10
American Journal of Epidemiology
54 training papers
11
Human Genetics and Genomics Advances
39 training papers
12
BMC Medicine
155 training papers
13
BMC Medical Research Methodology
41 training papers
14
European Journal of Epidemiology
36 training papers
15
Science Advances
52 training papers
16
Nature Genetics
72 training papers
17
Science
46 training papers
18
Communications Biology
36 training papers
19
Proceedings of the National Academy of Sciences
100 training papers
20
Epidemics
96 training papers
21
Epidemiology
26 training papers
22
Communications Medicine
63 training papers
23
Epidemiology and Infection
80 training papers
24
Statistics in Medicine
17 training papers
25
iScience
74 training papers
26
Frontiers in Genetics
32 training papers
27
eBioMedicine
82 training papers
28
Journal of Theoretical Biology
29 training papers
29
Nature
58 training papers
30
Nature Medicine
88 training papers