Back
Hypertension increases PPV for polycystic kidney disease in PKD1 and PKD2 variant carriers
Telis, N.; McEwen, L.; Bolze, A.; Judge, D.; Pawloski, P. A.; Hajek, C.; Schiabor Barrett, K.; Washington, N.; Cirulli, E. T.
2023-11-01
genetic and genomic medicine
10.1101/2023.10.30.23297693
medRxiv
Show abstract
Withdrawal StatementThis version of the manuscript and associated files have been removed owing to concerns of data privacy.
Matching journals
●Non-profit
◐University press
○Commercial
The top 9 journals account for 50% of the predicted probability mass.
1
Journal of the American Society of Nephrology
○
56 papers in training set
Top 0.2%
7.8%
Similar papers in this journal
- Clonal hematopoiesis of indeterminate potential contributes to accelerated chronic kidney disease progression 94%
- Prognostic Utility of Total Kidney Volume for Chronic Kidney Disease Risk Prediction: An Observational and Mendelian Randomization Study 94%
- Kidney single-cell atlas reveals myeloid heterogeneity in progression and regression of kidney disease. 93%
2
Nature Communications
○
5641 papers in training set
Top 22%
7.2%
Similar papers in this journal
- A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood 94%
- Exome-wide analysis of congenital kidney anomalies reveals new genes and shared architecture with developmental disorders 94%
- PKD1 and PKD2 mRNA cis-inhibition drives polycystic kidney disease progression 93%
3
Genome Medicine
○
183 papers in training set
Top 0.4%
6.6%
Similar papers in this journal
5
Journal of Clinical Investigation
●
179 papers in training set
Top 0.8%
5.4%
Similar papers in this journal
- Quantifying variant contributions in cystic kidney disease using national-scale whole genome sequencing 95%
- Post-ischemic inactivation of HIF prolyl hydroxylases in endothelium promotes maladaptive kidney repair by inducing glycolysis 92%
- Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis 92%
50% of probability mass above
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.