Polinton-like Viruses Associated with Entomopoxviruses Provide Insight into Replicon Evolution
Barth, Z. K.; Hicklin, I.; Theze, J.; Takatsuka, J.; Nakai, M.; Herniou, E. A.; Brown, A. M.; Aylward, F. O.
Show abstract
Polinton-like viruses (PLVs) are a diverse group of small integrative dsDNA viruses that infect diverse eukaryotic hosts. Many PLVs are hypothesized to parasitize viruses in the phylum Nucleocytoviricota for their own propagation and spread. Here we analyze the genomes of novel PLVs associated with the occlusion bodies of entomopoxvirus (EV) infections of two separate lepidopteran hosts. The presence of these elements within EV occlusion bodies suggests that they are the first known hyperparasites of poxviruses. We find that these PLVs belong to two distinct lineages that are highly diverged from known PLVs. These PLVs possess mosaic genomes, and some essential genes share homology with mobile genes within EVs. Based on this homology and observed PLV mosaicism, we propose a mechanism to explain the turnover of PLV replication and integration genes.
Matching journals
The top 3 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- Accumulated metagenomic studies reveal recent migration, whole genome evolution, and undiscovered diversity of orthomyxoviruses 97%
- Bipartite viral RNA genome heterodimerization influences genome packaging and virion thermostability 95%
- Swine H1N1 influenza virus variants with enhanced polymerase activity and HA stability promote airborne transmission in ferrets 95%
Similar papers in this journal
- Emerging SARS-CoV-2 diversity revealed by rapid whole genome sequence typing. 94%
- Novel high-quality amoeba genomes reveal widespread codon usage mismatch between giant viruses and their hosts 94%
- Mutational pressure drives differential genome conservation in two bacterial endosymbionts of sap feeding insects 92%
Similar papers in this journal
- Engineering, Decoding And Systems-Level Characterization Of Chimpanzee Cytomegalovirus 95%
- A novel ilarvirus protein is expressed via stop codon readthrough and suppresses RDR6-dependent RNA silencing 95%
- Aviadenovirus structure: a highly thermostable capsid in the absence of stabilizing proteins 95%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.