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Investigating markers of pulmonary aspiration in bronchoalveolar lavage from children with severe neurodisability
2023-10-03
pediatrics
Title + abstract only
View on medRxiv
Show abstract
Respiratory exacerbations are a frequent cause of hospitalisation in children with severe neurodisability (ND). Direct aspiration of food/saliva, reflux aspiration of gastric contents or a combination of both is thought to be a common cause of respiratory symptoms and disease, particularly when this occurs silently. A number of aspiration biomarkers, including bile acids and pepsin, have been proposed, however, no gold-standard diagnostic tests are currently available. In children with severe N...
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