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Age-related white matter differences in children with neurofibromatosis type 1 compared to controls

2023-09-29 neurology Title + abstract only
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Neurofibromatosis type 1 (NF1) is a common genetic condition in which 30-70% of children experience learning challenges including deficits in attention, executive function, and working memory. White matter pathways have been implicated in these cognitive functions; yet, they have not been well characterized in NF1. In this retrospective cohort study, we used diffusion MRI tractography to examine the microstructural properties of major white matter pathways in 20 children with NF1 aged 1 year to ...

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