Retrotransposon-driven environmental regulation of FLC leads to adaptive response to herbicide
Raingeval, M.; Leduque, B.; Baduel, P.; Edera, A.; Roux, F.; Colot, V.; Quadrana, L.
Show abstract
The mobilization of retrotransposons yields major-effect mutations. Here, we report an adaptive retrotransposon insertion within the first intron of the Arabidopsis floral-repressor locus FLOWERING LOCUS C (FLC). The insertion-mutation augments the environmental sensitivity of FLC by affecting the balance between coding and non-coding transcript isoforms in response to environmental threads. We show that this balance is modulated epigenetically by DNA methylation and orchestrated by IBM2, a factor involved in the processing of intronic heterochromatin. The stress-sensitive allele of FLC has recently spread across populations subjected to recurrent chemical weeding, and we demonstrate that retrotransposon-driven acceleration of life cycle represents a rapid response to herbicide. Our findings illustrate how retrotransposition can create environmentally-sensitive alleles that facilitate adaptation to anthropogenic disturbances of the environment.
Matching journals
The top 8 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Evolutionary Origins and Functional Diversification of Auxin Response Factors 94%
- A hierarchical transcriptional network activates specific CDK inhibitors that regulate G2 to control cell size and number in Arabidopsis 93%
- Interspecific introgression mediates adaptation to whole genome duplication 93%
Similar papers in this journal
- Histone H1 prevents non-CG methylation-mediated small RNA biogenesis in Arabidopsis heterochromatin 96%
- The Arabidopsis m6A-binding proteins ECT2 and ECT3 bind largely overlapping mRNA target sets and influence target mRNA abundance, not alternative polyadenylation 95%
- Combinations of maternal-specific repressive epigenetic marks in the endosperm control seed dormancy 95%
Similar papers in this journal
- Atypical epigenetic and small RNA control of degenerated transposons and their fragments in clonally reproducing Spirodela polyrhiza 96%
- Plant Polymerase IV sensitizes chromatin through histone modifications to preclude spread of silencing into protein-coding domains 95%
- Low ribosomal RNA genes copy number provoke genomic instability and chromosomal segment duplication events that modify global gene expression and plant-pathogen response 94%
Similar papers in this journal
- Genomic analyses of the Linum distyly supergene reveal convergent evolution at the molecular level 94%
- The diallelic self-incompatibility system in Oleaceae is controlled by a hemizygous genomic region expressing a gibberellin pathway gene 94%
- Regulation of hair cell and stomatal size by a hair-cell specific peroxidase in the grass Brachypodium distachyon 93%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.