Back

Comparisons of newborn birthweights with maternal factors at Phalombe District Hospital, Malawi: a retrospective record review

Mfipa, D.; Hajison, P. L.; Mpachika-Mfipa, F.

2023-09-06 public and global health
10.1101/2023.09.05.23295074 medRxiv
Show abstract

BackgroundBirthweight is an important indicator of the newborns future health. Maternal factors, including age, HIV status, parity and obstetric complications ([pre]-eclampsia, antepartum hemorrhage [APH] and sepsis), however, have been shown as risk factors of low birthweight (LBW). For data-guided interventions, we compared newborn birthweights with these factors at Phalombe District Hospital, Malawi. MethodsUsing a retrospective record review study design, we extracted data of 1,308 women and their newborns from maternity registers (October, 2022-March, 2023). Data were skewed. Its distribution in each group had different variabilities/shapes. We used Mann-Whitney U/Kruskal- Wallis H tests to compare mean rank of birthweights. ResultsPrevalence of LBW was 17.4% and median birthweight was 2,900.00g (interquartile range [IQR] 2,600.00g-3,200.00g). We observed significant difference in newborn birthweights among adolescent girls ([&le;]19 years), young women (20-24 years), older women (25-34 years) and women of advanced maternal age ([&ge;]35 years), (mean ranks: 600.32, 650.85, 690.62 and 735.34, respectively, H[3] = 20.30, p<.001, {eta}2 = 0.01). Pairwise comparisons showed significant differences in newborn birthweights of adolescent girls and older women (p = .006), adolescent girls and women of advanced maternal age (p<.001). We observed no significant differences in newborn birthweights between HIV+ and HIV- women (mean ranks: 608.86 and 659.28, respectively, U = 67,748.50, Z = -1.417, p = .157, r = 0.04). We found significant differences in newborn birthweights between primiparous and multiparous women (mean ranks: 600.95 and 697.16, respectively, U = 180,062.00, Z = -4.584, p<.001, r = 0.13), women with and women with no (pre)-eclampsia, APH and sepsis (mean ranks: 340.09 and 662.64, respectively, U = 10,662.00, Z = -4.852, p<.001, r=0.13). ConclusionSignificant differences reported notwithstanding, small effect sizes and a high prevalence of LBW were observed. Thus, all pregnant women should be prioritized to improve birthweight outcomes. Those with complications, however, require special care.

Matching journals

The top 2 journals account for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.