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How much should we sequence? An analysis of the Swiss SARS- CoV-2 surveillance effort
2023-08-31
public and global health
Title + abstract only
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BackgroundDuring the SARS-CoV-2 pandemic, many countries directed substantial resources towards genomic surveillance to detect and track viral variants. There is a debate over how much sequencing effort is necessary in national surveillance programs for SARS-CoV-2 and future pandemic threats. AimWe aimed to investigate the effect of reduced sequencing on surveillance outcomes in a large genomic dataset from Switzerland, comprising more than 143k sequences. MethodsWe employed a uniform downsamp...
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