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Phylogenies increase power to detect highly transmissible viral genome variants

2023-08-05 epidemiology Title + abstract only
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As demonstrated by the SARS-CoV-2 pandemic, the emergence of novel viral strains with increased transmission rates poses a significant threat to global health. Viral genome sequences, combined with statistical models of sequence evolution, may provide a critical tool for early detection of these strains. Using a novel statistical model that links transmission rates to the entire viral genome sequence, we study the power of phylogenetic methods--using a phylogenetic tree relating viral samples--a...

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