Identification of a recombinant human astrovirus type 5 strain from an acute gastroenteritis outbreak in Beijing, China
Mao, t.; Zhang, P.; Li, L.-l.; yang, m.; wang, y.; ma, y.; Li, D.-d.; li, j.; Duan, Z.-j.
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Two samples positive for the same strain (2103CP) of human astrovirus (HAstV) were identified during an acute gastroenteritis outbreak in Beijing, China. A full genomic analysis showed that for both samples, open reading frame 1a (ORF1a) clustered with HAstV-1, whereas ORF1b and ORF2 clustered with HAstV-5. The recombination site was detected upstream of the region where ORF1a and ORF1b overlapped. Recombinant HAstV-5 strains were reported previously in China in 2013 and 2021. Our results indicate the need for continuous surveillance of the prevalence and evolution of this recombinant HAstV-5 in China.
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