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Healthy adults possess cross-reactive neuraminidase inhibition antibodies to an A(H5N1) clade 2.3.4.4b avian influenza virus A/Black Faced Spoonbill/Hong Kong/AFCD-HKU-22-21429-01012/2022

Daulagala, P.; Cheng, S. M. S.; Chin, A. W. H.; Luk, L. L. H.; Leung, K.; Wu, J. T.; Poon, L. L. M.; Peiris, J. S. M.; Yen, H.-L.

2023-06-27 infectious diseases
10.1101/2023.06.23.23291839 medRxiv
Show abstract

Hemagglutination inhibition (HI) and neuraminidase inhibition (NI) antibodies to a clade 2.3.4.4b A(H5N1) highly pathogenic avian influenza virus were measured in 63 age-stratified healthy adults in Hong Kong. No HI antibody was detected; 61 subjects had detectable NI antibodies to A(H5N1). NI titers to A(H5N1) and A(H1N1)pdm09 viruses were correlated.

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