OpenSIM: open source microscope add-on for structured illumination microscopy
Hannebelle, M. T. M.; Raeth, E.; Leitao, S.; Lukes, T.; Pospisil, J.; Toniolo, C.; Venzin, O. F.; Chrisnandy, A.; Swain, P. P.; Ronceray, N.; Lutolf, M. P.; Oates, A. C.; Hagen, G. M.; Lasser, T.; Radenovic, A.; Mckinney, J. D.; Fantner, G. E.
Show abstract
Super-resolution techniques expand the abilities of researchers who have the knowledge and resources to either build or purchase a system. This excludes the part of the research community without these capabilities. Here we introduce the openSIM add-on to upgrade existing optical microscopes to Structured Illumination super-resolution Microscopes (SIM). The openSIM is an open-hardware system, designed and documented to be easily duplicated by other laboratories, making super-resolution modality accessible to facilitate innovative research. The add-on approach gives a performance improvement for pre-existing lab equipment without the need to build a completely new system.
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