STUSC: selection tests under size change
Wooding, S.
Show abstract
SummaryNatural selection leaves signatures in genetic diversity. A challenge in detecting these signatures is that demographic history can shape genetic variation in ways similar to selection, making their effects difficult to disentangle. STUSC takes a simulation based approach to the problem. It performs five widely used tests for natural selection, Tajimas D, Fu and Lis F and F*, and Fu and Lis D and D*, which ordinarily require the assumption of constant population size, under any size history. It also provides methods for generating their statistical distributions, allowing their responses to demography to be studied and past results to be evaluated. Availability and implementationSTUSC is written in Java, and is freely available at the authors website, woodinglab.org/stusc Contactswooding@ucmerced.edu
Matching journals
The top 8 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Influence of the mutation load on the genomic composition of hybrids between outcrossing and self-fertilizing species 92%
- BASE: a novel workflow to integrate non-ubiquitous genes in genomics analyses for selection. 91%
- Unidirectional response to bidirectional selection on body size. II Quantitative genetics. 90%
Similar papers in this journal
Similar papers in this journal
- Dsuite - fast D-statistics and related admixture evidence from VCF files 94%
- Commonly used Hardy-Weinberg equilibrium filtering schemes impact population structure inferences using RADseq data 94%
- slimr: An R package for integrating data and tailor-made population genomic simulations over space and time 93%
Similar papers in this journal
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.