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Bifrontal transcranial direct current stimulation normalises learning rate adjustment in low mood

2023-04-26 psychiatry and clinical psychology Title + abstract only
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BackgroundTranscranial direct current stimulation (tDCS) applied to dorsolateral prefrontal cortex has mild to moderate antidepressant effects. Little is known about the mechanisms of action. Other antidepressant treatments have been shown to act in part by reducing negative biases, which are thought to play a causal role in the maintenance of depression. Negative biases are hypothesized to stem from aberrant reinforcement learning processes, more precisely from overestimation of the informative...

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