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Preliminary clinical characteristics of Pediatric Covid-19 cases during the ongoing Omicron XBB.1.16 driven surge in a north Indian city

Vashishtha, V. M.; Kumar, P.

2023-04-20 infectious diseases
10.1101/2023.04.18.23288715 medRxiv
Show abstract

India is experiencing a new surge in Covid-19 cases in most parts of the country. A new sub-variant of Omicron, XBB.1.16 which is far more aggressive and immune evasive than other sub-lineages of Omicron, is responsible for this outbreak. In this preliminary account, we describe key clinical characteristics of SARS-CoV-2 infected children, visiting an outdoor department of a pediatric hospital in a north Indian city. Our preliminary findings show a higher involvement of young infants than older children and mild respiratory illness predominates other presentations. One interesting finding was the presence of itchy, non-purulent conjunctivitis with mucoid discharge and stickiness of eyelids in 42.8% of positive infants. None of the children required hospitalization. All recovered with symptomatic treatment. Key findingsO_LIThe current ongoing XBB.1.16 driven surge of Covid-19 is causing mild febrile illness in children in India C_LIO_LIYoung infants are disproportionately more affected than older children. C_LIO_LIUnlike the previous BA.2 Omicron wave, respiratory symptoms are predominating the clinical presentation in young infants in the ongoing surge. C_LIO_LIConjunctival involvement is seen in 42.8% of affected infants. C_LI

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