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SARS-CoV-2 post-vaccine surveillance studies in Australian children and adults with cancer: SerOzNET Statistical Analysis Plan

Body, A. L.; Martin, C.; Busija, L.; Lal, L.; Ahern, E. S.; MacIntyre, R. C.; Segelov, E.

2023-03-01 oncology
10.1101/2023.02.26.23286261 medRxiv
Show abstract

COVID-19 disease is associated with higher morbidity and mortality in cancer patients. Our study aimed to characterize the optimal strategy to improve vaccine induced protection against COVID-19 in children and adolescents with cancer. Results from The SerOzNET study will contribute comprehensive data on serology, cellular immune correlates from functional T-cell assays, quality of life data, and associated toxicity in relation to COVID-19 vaccination in children and adults with cancer. In this plan, we describe the statistics that will be used to report results of the SerOzNET study. SerOzNET examines COVID-19 vaccine response in children and adolescents with cancer. We have no conflicts of interest to disclose.

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