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MaGplotR: a software for the analysis and visualization of multiple MaGeCK screen datasets through aggregation

Matia, A.; Lorenzo, M. M.; Peng, D.

2023-01-16 bioinformatics
10.1101/2023.01.12.523725 bioRxiv
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MotivationMaGplotR analyzes multiple CRISPR screen datasets, identifies common hits, couples the hits to enrichment analysis and cluster plots, and produces publication-level plots. Output plots give information on the quality control of the screen data (e.g., sgRNA distribution) and show the best hits by aggregation from multiple screen experiments. To maximize comparability, rank is used to identify common hits. MaGplotR can also be used to analyze experiments where a control condition is used for multiple treatment conditions. MaGplotR is easy to use, with even just one argument. Availability and implementationMaGplotR is open-source code under MIT license. It is available at https://github.com/alematia/MaGplotR. Contactalejandro.matia@inia.csic.es

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"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.