Survey Design and Geospatial Analysis using Data on Baseline Prevalence, Environmental Risk-Factors and Treatment History Drastically Reduces the Cost of STH Impact Surveys.
Fronterre, C.; Johnson, O.; Giorgi, E.; Montresor, A.; Diggle, P. J.
Show abstract
Soil-transmitted helminth (STH) infections are among the most common neglected tropical diseases worldwide, causing high morbidity and mortality rates in endemic areas. STH impact assessment surveys provide information on the changing epidemiological situation so that control programme managers can adapt the frequency of any continuing preventive chemotherapy (PC). The cost associated with conducting these surveys is an important factor, especially in developing countries with severely limited financial resources. Using three case studies based on historical data on baseline prevalence, environmental risk-factors and treatment history from Kenya, Sierra Leone and Zimbabwe, we show that a model-based geostatistics approach drastically reduces the cost of STH impact surveys by comparison with a survey conducted according to the current WHO guidelines, whilst maintaining the same overall accuracy. The framework that we develop is disease-agnostic and could easily be repurposed for use with other NTDs.
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