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Genome-wide association study of longitudinal urinary albumin excretion in patients with type 1 diabetes
2022-12-19
endocrinology
Title + abstract only
View on medRxiv
Show abstract
Identifying genetic determinants for longitudinal changes in albumin excretion in individuals with type 1 diabetes may help identify those that are predisposed to renal, retinal and cardiovascular complications. Most studies have focussed on genetic predisposition to diabetic kidney disease and used cross-sectional measurements of urinary albumin excretion, but with limited success. Here, we utilise the wealth of longitudinal data and bio-samples collected from cohorts of childhood-onset type 1 ...
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