The role of human superior colliculus in affective experiences during visual and somatosensory stimulation
Chen, D.; Kragel, P. A.; Savoca, P. W.; Wald, L. L.; Bianciardi, M.; Wager, T. D.; Quigley, K. S.; Satpute, A. B.; Barrett, L. F.; Theriault, J. E.
Show abstract
The superior colliculus is often studied for its role in visually guided behaviors, but research in non-human animals indicates it is a midbrain hub for processing sensory information from multiple domains, including interoception (which is associated with affect). We used ultra-high field 7-Tesla fMRI to extend this work to humans, modeling superior colliculus BOLD signal intensity during visual or somatosensory stimulation (N = 40 in each sensory modality), both under aversive and neutral affective intensity. As hypothesized, the superior colliculus showed increased BOLD signal intensity in the dorsal and ventral subregions during visual and somatosensory stimulation, respectively. The entire superior colliculus also showed increased BOLD signal intensity during aversive compared to neural conditions. The superior colliculus BOLD signal intensity also correlated with a preregistered set of brain regions involved in visual, somatosensory, and interoceptive processing.
Matching journals
The top 3 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- Resolving multisensory and attentional influences across cortical depth in sensory cortices 96%
- Intrinsic timescales as an organizational principle of neural processing across the whole rhesus macaque brain 96%
- Mesoscale functional organization and connectivity of color, disparity, and naturalistic texture in human second visual area 96%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.