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Layer-dependent activity in the human superior colliculus during working memory

Chen, D.; Kragel, P. A.; Wager, T. D.; Wald, L. L.; Bianciardi, M.; Satpute, A. B.; Quigley, K. S.; Barrett, L. F.; Katsumi, Y.; Theriault, J. E.

2022-12-06 neuroscience
10.1101/2022.12.06.518975 bioRxiv
Show abstract

We examined the superior colliculus (SC) with ultra-high resolution 7-Tesla fMRI during an N-back working memory task. We observed both increased BOLD signal intensity and functional connectivity that followed a layer-dependent pattern predicted from anatomical connections between SC and other brain structures important for visual processing, motor control, and executive function. Our results highlight a role for the human SC in cognitive functions that usually associated with the cerebral cortex.

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