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Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population
2022-11-30
genetic and genomic medicine
Title + abstract only
View on medRxiv
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While 1-2% of individuals meet the criteria for a clinical diagnosis of obsessive-compulsive disorder (OCD), many more ([~]15-40%) experience subclinical obsessive-compulsive symptoms (OCS) during their life. To characterize the genetic underpinnings of OCS and its genetic relationship to OCD, we conducted the largest genome-wide association study (GWAS) meta-analysis of parent- or self-reported OCS to date (N = 33,943 with complete phenotypic and genome-wide data), combining the results from se...
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