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Homunculus Interruptus: A motor association area in the depth of the central sulcus

Jensen, M. A.; Huang, H.; Ojeda Valencia, G.; Klassen, B.; van den Boom, M.; Kaufmann, T.; Schalk, G.; Brunner, P.; Hermes, D.; Worrell, G.; Miller, K. J.

2022-11-21 neuroscience
10.1101/2022.11.20.517292 bioRxiv
Show abstract

Cells in the precentral gyrus of the human brain directly send signals to the periphery to generate movement and are topologically organized as a map of the body. We find that movement induced electrophysiological changes from implanted depth electrodes extend this map 3-dimensionally throughout the volume of the gyrus. Unexpectedly, this organization is interrupted by a motor association area in the depths of the central sulcus at its mid-lateral aspect that is active during many different types of movements from both sides of the body.

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