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Inferring a cell's capabilities from omics data with ImmCellFie

Masson, H. O.; Borland, D.; Reilly, J.; Telleria, A.; Shrivastava, S.; Watson, M.; Bustillo, L.; Li, Z.; Capps, L.; Kellman, B. P.; King, Z. A.; Richelle, A.; Lewis, N. E.; Robasky, K.

2022-11-17 bioinformatics
10.1101/2022.11.16.516672 bioRxiv
Show abstract

ImmCellFie is a user-friendly, web-based platform for comprehensive analysis of metabolic functions inferred from transcriptomic or proteomic data. It enables researchers to leverage the powerful mechanistic insight provided by complex genome-scale metabolic models with little to no bioinformatics training required. The platform has been integrated with a series of useful tools and richly annotated scientific visualizations for interactive exploration by the user. ImmCellFie pushes beyond simple statistical enrichment and incorporates complex biological mechanisms to quantify cell activity. Graphical abstract

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