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Cost-effectiveness of short, oral treatment regimens for rifampicin resistant tuberculosis

2022-11-10 health economics Title + abstract only
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IntroductionCurrent options for treating tuberculosis (TB) that is resistant to rifampicin (RR-TB) are few, and regimens are often long and poorly tolerated. Following recent evidence from the TB-PRACTECAL trial countries are considering programmatic uptake of 6-month, all-oral treatment regimens. MethodsWe used a Markov model to estimate the incremental cost-effectiveness of three regimens containing bedaquiline, pretomanid and linezolid (BPaL) with and without moxifloxacin (BPaLM) or clofazim...

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