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Sex-specific genetic loci linked to early and late onset type 2 diabetes
2022-10-27
endocrinology
Title + abstract only
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PurposeTo investigate the effect of sex and age on the timing of a type 2 diabetes (T2D) diagnosis and the influence T2D-related genes, parental history of T2D, and obesity on T2D development. MethodsIn this case-control study, 1012 T2D cases and 1008 healthy subjects were selected from the Diabetes in Mexico Study database. Participants were stratified by sex and age at T2D diagnosis (early, [≤]45 years; late, [≥]46 years). Seventy T2D-associated SNPs were explored and the percentage con...
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