Multiphase coexistence capacity in complex fluids
Shrinivas, K.; Brenner, M. P.
Show abstract
Complex fluids like the cytoplasm comprise hundreds of species organized into many coexisting phases. How molecular interactions, reflecting sequence, design, or functional constraints, dictate multiphase coexistence is a major open question. To answer this, we consider models of multicomponent fluids with both designed and random interactions. When crosstalk is introduced, we show that coexisting phases lose specificity beyond a common threshold. In a sequence model, we demonstrate that phase capacity is limited by sequence length and grows logarithmically/linearly with sequence length/number. These results provide a general route to program multiphase coexistence from molecular features.
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