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Neural representations of the content and production of human vocalization

Voigtlaender, V. A.; Sandhaeger, F.; Hawellek, D.; Hage, S. R.; Siegel, M.

2022-09-30 neuroscience
10.1101/2022.09.30.510259 bioRxiv
Show abstract

Speech, as the spoken form of language, is fundamental for human communication. The phenomenon of covert inner speech implies a functional independence of speech content and motor production. However, it remains unclear how a flexible mapping between speech content and production is achieved on the neural level. To address this, we recorded magnetoencephalography (MEG) in humans performing a rule-based vocalization task. On each trial, vocalization content (one of two vowels) and production form (overt or covert) were instructed independently. Using multivariate pattern analysis, we found robust neural information about vocalization content and production, mostly originating from speech areas of the left hemisphere. Production signals dynamically transformed upon presentation of the content cue, whereas content signals remained largely stable throughout the trial. In sum, our results show dissociable neural representations of vocalization content and production in the human brain and provide new insights into the neural dynamics underlying human vocalization.

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