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Study of the associations between short telomeres, sex hormones and pulmonary fibrosis

2022-09-30 respiratory medicine Title + abstract only
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BackgroundPulmonary fibrosis (PF) is an incurable fibrotic lung disease with limited treatment options and a high mortality. Evidence is growing that short telomeres cause both heritable and idiopathic pulmonary fibrosis (IPF). Based on survival data, we hypothesised that sex hormones are protective against premature telomere attrition and could influence PF disease onset and/or progression. MethodsAssociations between IPF, sex hormone concentrations and measured leukocyte telomere length (LTL)...

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