In vivo CRISPR screen defines Slc25a37 as an organ-specific regulator of antioxidant metabolism in metastasis
Cuadros, A. M.; Fernandez-Garcia, J.; Planque, M.; Altea-Manzano, P.; Schalley, T.; Vermeire, I.; Broekaert, D.; Wu, Q.; Van Brussel, T.; Leduc, S.; Maetens, M.; Nguyen, H.-L.; Van Baelen, K.; Darzi, N.; Floris, G.; Wildiers, H.; Desmedt, C.; Lambrechts, D.; Fendt, S.-M.
Show abstract
Withdrawal StatementThe authors have withdrawn their manuscript owing to the detection of inaccurate data analysis in some figure panels that leads in some but not all cases to a different interpretation of the data after corrected analysis. Therefore, the authors do not wish this work to be cited as reference for the project. If you have any questions, please contact the corresponding author.
Matching journals
The top 6 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Mitochondrial complex III deficiency drives c-MYC overexpression and illicit cell cycle entry leading to senescence and segmental progeria 92%
- FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell 91%
- NAD+ repletion with niacin counteracts cancer cachexia 91%
Similar papers in this journal
Similar papers in this journal
- Identifying a gene signature of metastatic potential by linking pre-metastatic state to ultimate metastatic fate 91%
- Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors 91%
- Hypoxia-inducible factor 1 protects neurons from Sarm1-mediated neurodegeneration 91%
Similar papers in this journal
- PCK1 and DHODH drive colorectal cancer liver metastatic colonization and nucleotide biosynthesis under hypoxia 91%
- Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer 91%
- S100a4+ alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting the angiogenic function regulated by fatty acid metabolism 90%
Similar papers in this journal
- Murine breast cancers disorganize the liver transcriptome in zonated manners 90%
- Neutrophil Extracellular Trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting metastasis of pancreatic tumours 90%
- Ribonucleotide Reductase Subunit Switching in Hepatoblastoma Drug Response and Relapse 90%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.