Lateral line hair cells integrate mechanical and chemical cues to orient navigation
Desban, L.; Roussel, J.; Mirat, O.; Lejeune, F.-X.; Keiser, L.; Michalski, N. A.; Wyart, C.
Show abstract
The lateral line is a superficial sensory system responding to environmental hydrodynamic changes to orient locomotion of aquatic vertebrate species. Whether this system also detects chemical cues is unknown. We find that zebrafish lateral line hair cells express numerous chemoreceptors, including ionotropic receptors for serotonin. We show that the serotonin enriched in skin neuroepithelial cells is released upon injury and that environmental serotonin activates lateral line hair cells. We show that larval zebrafish exposed to serotonin in their environment rely on the lateral line to swim fast and away. These results uncover the sensory versatility of lateral line hair cells and how these properties modulate navigation in response to environmental stimuli.
Matching journals
The top 3 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Functional and ultrastructural analysis of reafferent mechanosensation in larval zebrafish 97%
- Polymodal sensory perception of mechanical and chemical cues drives robust settlement and metamorphosis of a marine pre-vertebrate zooplanktonic larva. 96%
- Larval zebrafish use olfactory detection of sodium and chloride to avoid salt-water 96%
Similar papers in this journal
Similar papers in this journal
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.