Costing analysis to introduce a Contrast Enhanced Mammography service in place of existing breast MRI service for local staging of breast cancer
Savaridas, S.; Jin, H.
Show abstract
IntroductionContrast-enhanced spectral mammography (CESM) is a functional imaging technique with comparable accuracy to MRI for loco-regional staging of breast cancer. This study assesses the cost impact of switching from CE-MRI to CESM for loco-regional staging of breast cancer from a public healthcare perspective. MethodsThe CE-MRI cost was obtained from NHS reference cost. The CESM cost was calculated using a bottom-up approach including use of the machine, pump injector, contrast, image storage and clinical staffs time for reporting and cannulation. The cost of upgrading existing machines to CESM or purchasing new mammographic machines were obtained via national procurement. Other costs were obtained from local pharmacy, published unit cost data, or estimated based on surveys. ResultsFor large health boards in Scotland ([≥]500 cancers diagnosed/annum), the cost savings of switching from CE-MRI to CESM range from {pound}64,069 to {pound}81,570. For small health boards (<500 cancers diagnosed/annum), the cost savings of switching from CE-MRI to CESM range from {pound}6,453 to {pound}23,953. The cost savings are most sensitive to the number of tests conducted per year, and whether the existing mammography machine can be upgraded to CESM or not. ConclusionSwitching from CE-MRI to CESM for loco-regional staging of breast cancer is likely to be cost saving for both large and small health boards in Scotland. Further research is urgently needed to confirm the non-inferiority of CESM to CE-MRI as a locoregional staging technique. The input data of this analysis can be updated when such results become available. HighlightsO_LISwitching from CE-MRI to CESM for locoregional staging is likely to be cost saving C_LIO_LIFor large health boards, estimated annual savings range from {pound}64,069 to {pound}81,570 C_LIO_LIFor a small health boards, estimated annual savings range from {pound}6,453 to {pound}23,953 C_LIO_LICost is driven by number of imaging studies and equipment upgrade vs replacement C_LIO_LIResearch to confirm the non-inferiority of CESM for locoregional staging is needed C_LI
Matching journals
The top 7 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Development and validation of multivariable machine learning algorithms to predict risk of cancer in symptomatic patients referred urgently from primary care 90%
- Palliative care in the treatment of women with breast cancer: a scoping review protocol 89%
- Understanding preferences for self-sampling in a national cervical screening programme: a protocol for a discrete choice experiment 88%
Similar papers in this journal
- BREAst screening Tailored for HEr (BREATHE) - A Study Protocol On Personalised Risk-based Breast Cancer Screening Programme 92%
- Improved accuracy of breast volume calculation from 3D surface imaging data using statistical shape models 91%
- Evaluation of the efficacy of using indocyanine green associated with fluorescence in sentinel lymph node biopsy 91%
Similar papers in this journal
- Mammographic density assessed using deep learning in women at high risk of developing breast cancer: the effect of weight change on density 92%
- Model uncertainty estimates for deep learning mammographic density prediction using ordinal and classification approaches 90%
- Breast density prediction from low and standard dose mammograms using deep learning: effect of image resolution and model training approach on prediction quality 87%
Similar papers in this journal
- RNA expression classifiers from a model of breast epithelial cell organization to predict pathological complete response in triple negative breast cancer 87%
- AI-based image quality assessment in CT 86%
- What is the value of community oximetry monitoring in people with SARS-CoV-2? – A prospective, open-label clinical study 82%
Similar papers in this journal
- Novel mammogram-based measures improve breast cancer risk prediction beyond an established mammographic density measure 90%
- Reproductive Factors and Risk of Breast Cancer by Tumor Subtypes among Ghanaian Women: A Population-based Case-control Study 88%
- Prelude to Malignancy: A Gene Expression Signature in Normal Mammary Gland from Breast Cancer Patients Suggests Pre-tumorous Alterations and Is Associated with Adverse Outcomes 87%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.