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Importance of external validation and subgroup analysis in artificial-intelligence detecting low ejection fraction from electrocardiograms
2022-07-24
cardiovascular medicine
Title + abstract only
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IntroductionAsymptomatic left ventricular dysfunction (ALVD) carries an increased risk for overt heart failure and mortality, yet treatable to mitigate disease progression. An artificial intelligence (AI)-enabled 12-lead electrocardiogram (ECG) model demonstrated promise in ALVD screening but an unexpected drop in performance was observed in external validation. We thus sought to train a de novo model for ALVD detection and investigate its performance across multiple institutions and across a br...
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