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Genomic evidence for ancient migrations routes along South America's Atlantic coast

dos Santos, A. L. C.; Owings, A.; Sullasi, H. S. L.; Gokcumen, O.; DeGiorgio, M.; Lindo, J.

2022-06-30 genomics
10.1101/2022.06.27.497820 bioRxiv
Show abstract

An increasing body of archaeological and genomic evidence has hinted to a complex settlement process of the Americas. This is especially true for South America, where unexpected ancestral signals have raised perplexing scenarios for the early migrations into different regions of the continent. Here we present ancient genomes from the archaeologically rich Northeast Brazil and compare them to ancient and present-day genomic data. We find a distinct relationship between ancient genomes from Northeast Brazil, Lagoa Santa, Uruguay and Panama, representing evidence for ancient migration routes along South Americas Atlantic coast. To further add to the existing complexity, we also detect greater Denisovan than Neanderthal ancestry in ancient Uruguay and Panama individuals. Moreover, we find a strong Australasian signal in an ancient genome from Panama. This work sheds light on the deep demographic history of eastern South America and presents a starting point for future fine-scale investigations on the regional level.

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