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Single-shot off-axis full-field optical coherence tomography

Martins Seromenho, E.; Marmin, A.; Facca, S.; Bahlouli, N.; Perrin, S.; Nahas, A.

2022-06-03 biophysics
10.1101/2022.06.02.494183 bioRxiv
Show abstract

Full field optical coherence tomography (FF-OCT) enables high-resolution in-depth imaging within turbid media. In this work, we present a simple approach which combines FF-OCT with off-axis interferometry for the reconstruction of the en-face images. With low spatial and temporal coherence illumination, this new method is able to extract an FF-OCT image from only one interference acquisition. This method is described and the proof-of-concept is demonstrated through the observation of scattering samples such as organic and ex-vivo biomedical samples.

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