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Phenomic Network Analysis for Depression Reveals Comorbidity Architecture, Genomic Relationships, and Pleiotropic Variants

2022-05-16 genetic and genomic medicine Title + abstract only
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Depression is one of the most prevalent psychiatric disorders and is one of the leading causes of health ailment worldwide. It is known to be highly heritable and is frequently comorbid with other mental and physical traits. This observation motivated us to look deeper into the genetic and phenotypic connections between depression and other traits in order to identify correlations as well as potentially causal connections between them. In this study, we analyzed data from the UK biobank to syste...

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