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Cancer-associated Lactobacillus iners are genetically distinct and associated with chemoradiation resistance in cervical cancer
2022-04-28
oncology
Title + abstract only
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This study identifies a novel pathotype of cervical cancer-associated Lactobacillus iners (L. iners) that results in chemoradiation resistance in vitro and is associated with poor patient survival. Cervical cancer affects over half a million women a year around the world. Treatment for women with locally advanced cancer is delivered with definitive chemoradiation (CRT) but is curative for only 60% of patients. There are few validated molecular markers to identify patients who will respond poorly...
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