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A systematic review of the reporting and methodological quality of studies that use Mendelian randomisation in UK Biobank
2022-04-26
epidemiology
Title + abstract only
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BackgroundMendelian randomisation (MR) is a method of causal inference that uses genetic variation as an instrumental variable (IV) to account for confounding. While the number of MR articles published each year is rapidly rising (partly due to large cohort studies such as the UK Biobank making it easier to conduct MR), it is not currently known whether these studies are appropriately conducted and reported in enough detail for other researchers to accurately replicate and interpret them. Metho...
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