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Air pollution exposure and mitochondrial DNA copy number in the UK Biobank
2022-04-19
epidemiology
Title + abstract only
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BackgroundLow levels of mitochondrial DNA copy number (mtDNA-CN) are a biomarker of mitochondrial dysfunction often induced by oxidative stress. Air pollution is a pervasive source of oxidative stress, but the association between air pollution exposure and mtDNA-CN is inconclusive. ObjectiveWe evaluated the association between long-term exposure to PM [≤] 10 {micro}m diameter (PM10) and nitrogen dioxide (NO2) with mtDNA-CN in 195,196 adults in the UK Biobank study. MethodsAnnual average PM1...
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