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Proteomic Fingerprinting: A novel privacy concern

2022-04-12 genetic and genomic medicine Title + abstract only
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IntroductionPrivacy protection is a core principle of genomic research but needs further refinement for high-throughput proteomic platforms. MethodsWe identified independent single nucleotide polymorphism (SNP) quantitative trait loci (pQTL) from COPDGene and Jackson Heart Study (JHS) and then calculated genotype probabilities by protein level for each protein-genotype combination (training). Using the most significant 100 proteins, we applied a naive Bayesian approach to match proteomes to gen...

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