Potency and Breadth of Neutralization after 3 doses of mRNA vaccines in COVID-19 Convalescent and Naive individuals
Luczkowiak, J.; Rivas, G.; Labiod, N.; Lasala, F.; Rolo, M.; Lora-Tamayo, J.; Mancheno-Losa, M.; Rial-Crestelo, D.; Folgueira, M. D.; Delgado, R.
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Third doses of mRNA COVID-19 vaccines induced a significant increase in neutralizing potency and breadth in naive individuals comparable with convalescents who restored levels after the first two doses. These results suggest a limit to elicit neutralization in the number of stimuli by infection or vaccination with ancestral SARS-CoV-2 sequences
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