Back

GWAS and meta-analysis identifies multiple new genetic mechanisms underlying severe Covid-19.

2022-03-07 intensive care and critical care medicine Title + abstract only
View on medRxiv
Show abstract

Pulmonary inflammation drives critical illness in Covid-19, 1;2 creating a clinically homogeneous extreme phenotype, which we have previously shown to be highly efficient for discovery of genetic associations. 3;4 Despite the advanced stage of illness, we have found that immunomodulatory therapies have strong beneficial effects in this group. 1;5 Further genetic discoveries may identify additional therapeutic targets to modulate severe disease. 6 In this new data release from the GenOMICC (Genet...

Predicted journal destinations

1
Nature Communications
483 training papers
Top 0.9% 22.8%
2
Nature
58 training papers
#1 8.0%
3
eLife
262 training papers
Top 2% 8.0%
4
iScience
74 training papers
#1 6.6%
5
Genome Medicine
56 training papers
Top 1% 6.1%
6
Scientific Reports
701 training papers
Top 43% 6.1%
7
Nature Genetics
72 training papers
Top 4% 5.2%
8
Frontiers in Immunology
140 training papers
Top 6% 2.0%
9
Nature Medicine
88 training papers
Top 2% 2.0%
10
PLOS ONE
1737 training papers
Top 92% 2.0%
11
JCI Insight
63 training papers
Top 4% 1.6%
12
BMC Medicine
155 training papers
Top 16% 1.6%
13
PLOS Computational Biology
141 training papers
Top 9% 1.4%
14
Communications Biology
36 training papers
Top 2% 1.4%
15
European Respiratory Journal
44 training papers
Top 3% 1.4%
16
eBioMedicine
82 training papers
Top 7% 1.2%
17
The Journal of Infectious Diseases
137 training papers
Top 12% 1.2%
18
Critical Care Explorations
15 training papers
Top 1% 1.2%
19
Science Translational Medicine
40 training papers
Top 3% 1.0%
20
PLOS Genetics
39 training papers
Top 7% 1.0%
21
Proceedings of the National Academy of Sciences
100 training papers
Top 15% 1.0%
22
JAMA Network Open
125 training papers
Top 23% 1.0%
23
Frontiers in Medicine
99 training papers
Top 18% 1.0%
24
American Journal of Respiratory and Critical Care Medicine
23 training papers
Top 2% 0.7%
25
ERJ Open Research
36 training papers
Top 3% 0.7%
26
Cell Reports Medicine
49 training papers
Top 7% 0.7%
27
Journal of Translational Medicine
21 training papers
Top 1% 0.5%
28
BMJ
49 training papers
Top 9% 0.5%
29
The American Journal of Human Genetics
77 training papers
Top 8% 0.5%