Intracranial EEG spectral feature analysis and focal brain stimulation reveal affective specialization within dorsal anterior cingulate cortex
Metzger, B. A.; Kalva, P.; Mocchi, M. M.; Cui, B.; Adkinson, J. A.; Wang, Z.; Mathura, R.; Gavvala, J.; Krishnan, V.; Lin, L.; Maheshwari, A.; Shofty, B.; Sheth, S. A.; Bijanki, K. C. R.
Show abstract
Emotion is represented in several limbic and prefrontal cortical brain areas herein referred to as the Affective Salience Network (ASN). Within this network, less is known about how valence and intensity are processed in the dorsal anterior cingulate (dACC), and how affective processes in dACC compare to activity in other nodes within the ASN. Using a novel spectral feature approach to analyze intracranial electrophysiological data, we discover hemispheric specialization in the dACC such that the right hemisphere is sensitive to intensity while the left hemisphere is sensitive to valence and negative affective bias. We further applied 130 Hz continuous stimulation to the anterior cingulum bundle while patients viewed emotional faces. Faces were rated happier in all patients, an effect modulated by baseline affective bias, suggesting a causal role for the dACC during the processing of external affective stimuli.
Matching journals
The top 9 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Lateral Prefrontal Theta Oscillations Causally Drive a Computational Mechanism Underlying Conflict Expectation and Adaptation 96%
- Rhythmic interactions between the mediodorsal thalamus and prefrontal cortex precede human visual perception 96%
- Propofol Disrupts the Functional Core-Matrix Architecture of the Thalamus in Humans 95%
Similar papers in this journal
- Intrinsic neural timescales in the temporal lobe support an auditory processing hierarchy 95%
- Predictive feedback, early sensory representations and fast responses to predicted stimuli depend on NMDA receptors 94%
- Signatures of electrical stimulation driven network interactions in the human limbic system 94%
Similar papers in this journal
- Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice 96%
- Intracranial human recordings reveal intensity coding for the pain of others in the insula 95%
- Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women 95%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.