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Novel AlphasynucleinPAN in human Mesenchymal Stem Cells-derived neurons masks SNCA140 and creates dissociation of deleterious SNCA98 in astrocytoma stem cells
owoola, A. G.; Okolicsanyi, R. K.; Griffiths, L. R.; Haupt, L. M.
2022-04-06
neuroscience
10.1101/2022.02.08.479501
bioRxiv
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This manuscript has been withdrawn by the authors as it was submitted and made public without the full consent of all the authors. If you have any questions, please contact the corresponding author.
Matching journals
●Non-profit
◐University press
○Commercial
The top 14 journals account for 50% of the predicted probability mass.
1
EMBO Molecular Medicine
○
95 papers in training set
Top 0.1%
10.0%
Similar papers in this journal
- Enhanced Notch dependent gliogenesis and delayed physiological maturation underlie neurodevelopmental defects in Lowe syndrome 92%
- LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies 91%
- Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile 91%
2
Glia
○
81 papers in training set
Top 0.2%
8.0%
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- hiPSC-derived astrocytes from individuals with schizophrenia induce a dystrophic phenotype in microglial-like cells 93%
- C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC- Derived Microglia and Modulates Glial-Neuronal Crosstalk 92%
- Deletion induced splicing in RIC3 drives nicotinic acetylcholine receptor regulation with implications for endoplasmic reticulum stress in human astrocytes 92%
3
Cell Reports
○
1498 papers in training set
Top 8%
4.5%
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- Oxysterol-liver X receptor signaling mediates CYFIP1 regulation of cortical neurogenesis 92%
- ciRS-7 and miR7 regulate ischemia induced neuronal death via glutamatergic signaling 91%
- Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through cAMP/PKA pathway 91%
4
Nature Communications
○
5641 papers in training set
Top 33%
3.6%
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- Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype 92%
- Schwann cell plasticity regulates neuroblastic tumor cell differentiation via epidermal growth factor-like protein 8 91%
- Targeted Antisense Oligonucleotide Treatment Rescues Developmental Alterations in Spinal Muscular Atrophy Organoids 91%
5
Cells
○
249 papers in training set
Top 0.9%
3.3%
Similar papers in this journal
- Cockayne syndrome patient iPSC-derived brain organoids and neurospheres show early transcriptional dysregulation of biological processes associated with brain development and metabolism. 92%
- Rapid generation of ventral spinal cord-like astrocytes from human iPSCs for modeling non-cell autonomous mechanisms of lower motor neuron disease 92%
- Impaired p53-mediated DNA damage response contributes to microcephaly in Nijmegen Breakage Syndrome patient-derived cerebral organoids 91%
50% of probability mass above
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.