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Network Constraints on Longitudinal Grey Matter Changes in First Episode Psychosis

2022-01-12 psychiatry and clinical psychology Title + abstract only
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ImportancePsychotic illness is associated with anatomically distributed grey matter reductions that can worsen with illness progression, but the mechanisms underlying the specific spatial patterning of these changes is unknown. ObjectiveTo test the hypothesis that brain network architecture constrains cross-sectional and longitudinal grey matter alterations across different stages of psychotic illness and to identify whether certain brain regions act as putative epicentres from which volume los...

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