Back

Preferential expansion of cross-reactive pre-existing switched memory B cells that recognize the SARS-CoV-2 Omicron variant Spike protein

2022-01-01 allergy and immunology Title + abstract only
View on medRxiv
Show abstract

In previously unvaccinated and uninfected individuals, non-RBD SARS-CoV-2 spike-specific B cells were prominent in two distinct, durable, resting, cross-reactive, "pre-existing" switched memory B cell compartments. While pre-existing RBD-specific B cells were extremely rare in uninfected and unvaccinated individuals, these two pre-existing switched memory B cell compartments were molded by vaccination and infection to become the primary source of RBD-specific B cells that are triggered by vaccin...

Predicted journal destinations

1
Nature Communications
483 training papers
Top 2% 21.7%
2
Frontiers in Immunology
140 training papers
Top 0.6% 11.5%
3
Journal of Clinical Investigation
50 training papers
Top 0.2% 6.3%
4
Cell Reports Medicine
49 training papers
Top 0.1% 5.4%
5
eLife
262 training papers
Top 7% 5.4%
6
Cell
28 training papers
#1 4.9%
7
Science Immunology
15 training papers
#1 4.9%
8
The Journal of Immunology
19 training papers
Top 0.2% 4.1%
9
JCI Insight
63 training papers
Top 2% 3.8%
10
Proceedings of the National Academy of Sciences
100 training papers
Top 4% 2.7%
11
Cell Reports
25 training papers
Top 0.3% 1.9%
12
PLOS ONE
1737 training papers
Top 93% 1.9%
13
Nature Medicine
88 training papers
Top 3% 1.9%
14
eBioMedicine
82 training papers
Top 2% 1.9%
15
iScience
74 training papers
Top 3% 1.9%
16
npj Vaccines
18 training papers
#1 1.9%
17
Vaccine
140 training papers
Top 5% 1.5%
18
Cell Genomics
34 training papers
Top 6% 1.1%
19
Scientific Reports
701 training papers
Top 93% 0.9%
20
Science Translational Medicine
40 training papers
Top 3% 0.9%
21
Vaccines
131 training papers
Top 11% 0.9%
22
Communications Biology
36 training papers
Top 3% 0.9%
23
The Journal of Infectious Diseases
137 training papers
Top 14% 0.9%
24
PLOS Computational Biology
141 training papers
Top 15% 0.7%
25
Clinical Infectious Diseases
219 training papers
Top 27% 0.7%
26
Science Advances
52 training papers
Top 6% 0.7%
27
Annals of the Rheumatic Diseases
23 training papers
Top 1% 0.7%
28
Nature
58 training papers
Top 11% 0.7%