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Structural flexibility of the SARS-CoV-2 genome relevant to variation, replication, pathogenicity, and immune evasion.

Patarca, R.; Haseltine, W. A.

2021-12-21 microbiology
10.1101/2021.12.20.473542 bioRxiv
Show abstract

The SARS-CoV-2 pandemic continues to be driven by viral variants. Most research has focused on structural proteins and on site-specific mutations. Here, we describe recombination events involving genomic terminal sequences in SARS-CoV-2 and related viruses leading to structural rearrangements in terminal and coding regions and discuss their potential contributions to viral variation, replication, pathogenicity, and immune evasion.

Matching journals

The top 6 journals account for 50% of the predicted probability mass.

1
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9
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10
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13
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14
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17
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Top 7%
1.1%
19
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Top 11%
1.1%
20
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Top 0.9%
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Top 0.6%
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22
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Top 8%
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"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.