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Analysis of cutoff point estimation for determining seropositivity in the context of SARS-CoV-2 infections

Domingues, T. D.; Mourino, H.; Sepulveda, N.

2021-12-21 epidemiology
10.1101/2021.12.20.21268100 medRxiv
Show abstract

In this work will apply mixture models based on distributions from the SMSN family to antibody data against four SARS-CoV-2 virus antigens. Furthermore, since the true infection status of individuals is known a priori, performance measures will be calculated for the methods proposed for cutoff point estimation such as sensitivity, specificity and accuracy. The results of a simulation study will also be presented.

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"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.